pCLAMP Data Acquisition and Analysis software is the data acquisition and analysis software suite from the Axon Instruments Conventional Electrophysiology product line of Molecular Devices. Designed for a variety of experiments, pCLAMP software has become the standard for electrophysiological experimentation and analysis. The flexibility of the pCLAMP software allows researchers to adapt it to many uses outside its traditional applications in electrophysiology. The pCLAMP software suite contains the following: Clampex Software, for data acquisition and production of stimulus waveforms. Clampfit Software, for data analysis. AxoScope software, for background chart recording.
Features of the pCLAMP 11 (Standard)
- Design advanced protocols easily: The enhanced protocol editor enables up to 50 epochs instead of 10, providing the flexibility to program longer, more sophisticated protocols.
- Enhanced gap-free mode: A simple continuous "chart-recorder" useful for monitoring single channel events, minis, and other spontaneous activities. Protocol-editor-style epochs and program digital or analog outputs can be executed.
- Population spike analysis: This tool automatically calculates amplitude, area under the curve, half-width, decay and rise time, decay and rise slope, coastline of spike, and paired pulses.
- Action potential analysis: This feature automatically detects and analyzes amplitude, APD90, rise and decay time, rise and decay slope, peak-to-peak frequency and time, and more.
- Comprehensive analysis tools: The software includes a wealth of analysis tools including 24 cursor pairs for regions of interest search, graph plotting tools such as I-V plot and histogram, and more.
- Batch analysis: Macros for batch analysis eliminates the need to define parameters for every data set. Saved macros can be applied to multiple data sets for automatic analysis.
- Improved visualization: The membrane test window displays up to eight channels simultaneously, making it easier to control multiple channels.
- Streamline workflows: Batch analysis macros enable the analysis of data files in batches and eliminates the need to define parameters for every data set.
- Analyze faster: Automated event detection analyzes spontaneous and evoked action potentials and post-synaptic data. Identify events based on a variety of factors.
Sophisticated patch-clamp electrophysiology data acquisition and analysis software clampfit 11 offers 24 cursor pairs to select regions of interest as well as 1 pair for baseline region, summing to 25 pairs total.
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Standard pClamp 11
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Number pairs for region of interest search
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24 cursor pairs
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Number pairs for baseline region
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1 cursor pair
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TOTAL
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25 cursor pairs
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Specifications & Options of pCLAMP 11 Software Suite
Operating system-- minimum: Windows 10 Pro (32-bit)
Recommended: Windows 10, 11 Pro (32- or 64-bit)
CPU—Minimum: PC with 2 GHz processor
Recommended: PC with 2.0 GHz (or faster) Duo Processor
RAM—Minimum: 1.2 GB RAM
Recommended: 4 GB or higher
Display--Minimum: 1440 x 900 display
Recommended: 1920 x 1080 display or higher
Ports--Minimum: 1 USB 1 port (for security key dongle), 1 USB 2.0 port (for Digidata digitizers)
Recommended: 3 USB 2.0 ports
Compatible instruments
- Digidata 1550B 8-Channel Digitizer
- Digidata 1440A 16-Channel Digitizer
- MiniDigi 1B Two-Channel Digitizer
- Axoclamp 900A Microelectrode Amplifier
- Axopatch 200B Microelectrode Amplifier
- MultiClamp 700B Microelectrode Amplifier
- Most BNC-telegraphed amplifiers also supported
ADDITION INFORMATION; the price for new software is $6,000 ; compare it to our price.
Axon pCLAMP, Axon, DigiData and Windows Operating System Compatibility Table
Consult the table below to determine pCLAMP software compatibility with various AXON digitizers and Windows operating systems.
pCLAMP
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MiniDigi
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DigiData 1200
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DigiData 132x
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DigiData 1440
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Digidata 1550 series
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Windows OS
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8.x
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No
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Yes
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Yes
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No
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No
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95, 98, ME, NT4.0, 2000, XP
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9.x
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Yes
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Yes
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Yes
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No
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No
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98, ME, 2000, XP
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10.x
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Yes
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No
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Yes
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Yes
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Ye
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2000, XP sp3, Vista, Windows 7 & Windows 10e (32 & 64-bit)
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11.x
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Ye
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No
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No
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Yes
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Yes
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Windows 7 & Windows 10e (32 & 64-bit)
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Notes:
- Only U.S. versions of Windows operating systems are fully supported, and only a computer with authentic Windows is supported, i.e., emulators and virtual machines are not supported. pCLAMP version 10.3 or higher are the only installers that support 64-bit Operating Systems.
- Update from 8.0 or 8.1 to 8.2 is free. Only the 32-bit installer of 8.2 runs on Windows XP
- Update from 9.0 or 9.1 to 9.2 is free. pCLAMP 9 software is not supported for use under Windows 7 (32- or 64-bit versions).
- All updates within 10.x (e.g. from 10.0 to 10.7) are free.
- Windows Home Edition is not supported.
- Digidata 1440, 1550, 1550A, and 1550B are supported on 10.7.
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