FLUXION IonFlux HT automated patch clamp system

Fluxion IonFlux HT Automated Patch Clamp System (Used, Tested, Fully Operational)

You are purchasing a used Fluxion IonFlux HT Automated Patch Clamp System, the highest throughput automated patch clamp system available today. With 64 independent patch clamp amplifiers running in parallel, the system can produce up to 8,000 data points per day and is ideal for high-throughput ion channel research, drug screening, pharmacology studies, and cardiac safety profiling (e.g., hERG testing). The IonFlux HT can accommodate 384-well plates, enabling even larger experiments and increasing throughput.

✅ Condition:Used, fully operational, and in excellent working order.
✅ Guarantee: Fully functional and ready for use.

Key Features:

• Highest Throughput Available:
  With 64 patch clamp amplifiers running in parallel, the IonFlux HT delivers up to 8,000 data points per day, making it perfect for high-throughput screening of ion channels, drug screening, and cardiac safety profiling.
• Supports 384-Well Plates:
  The IonFlux HT is compatible with 384-well plates, allowing you to run even larger experiments and obtain data for 384 unique compounds with higher throughput per plate.
• Economic Data Collection:
  Offers the lowest cost per data point, making it the most cost-effective solution for large-scale ion channel research and drug discovery.
• Flexible Assay Options:
  Supports both ligand-gated and voltage-gated assays, providing flexibility to perform a wide range of ion channel assays with ease.
• Streamlined Automated Workflow:
  Offers plate reader simplicity, minimizes manual intervention, and integrates seamlessly with automated lab systems, significantly increasing experimental throughput and reproducibility.
• Compact Design:
  With a compact footprint (20" x 20" x 10"), the system fits easily into any lab, saving valuable space without compromising on performance.
• Fast Compound Application (<100ms):
  Compound application time is less than 100ms, enabling rapid compound exchange and perfect for specialized assays like ligand binding, allosteric modulation, and multi-agonist assays.
• 96-Well or 384-Well Plate Format:
  The system supports both 96-well and 384-well SBS format plates, offering 128 data points per plate and allowing you to test up to 64 unique compounds and 8 experimental patterns per plate.

System Specifications:

• Daily Throughput:
  Up to 8,000 data points per day with 64 amplifier channels.
• Cell Recording Configuration:
  Ensemble recording with 20 cells per ensemble and 2X redundancy.
• Amplifier Configuration:
  Adjustable sampling rate up to 20 kHz with capacitance, leak, and series resistance compensation for accurate and reliable data collection.
• Temperature Control:
  Ambient to 40ºC for a wide range of ion channel assays, including temperature-sensitive studies.
• Software:
  Includes protocol editor, assay development mode, run table, data visualization, and data export features. Compatible with Windows 7, XP, and Vista.
• External Compatibility:
• Compatible with most liquid handlers.
• Multiplexing: Integrates up to 4 readers per liquid handler.

System performance

Daily throughput: 2000 data point

Number of simultaneous amplifier channels:16

Cell recording configuration; Ensemble recording

Compound application time: <100ms

Plate format

Plate type:96-well, SBS format

Total data points per plate:128

Unique compounds/concentrations per plate:64

Number of experimental patterns per plate: 8

System Specifications Common to IonFlux 16 and IonFlux HT

Instrument configuration

 Instrument dimensions: 20” (50 cm) X 20” (50cm) X 10” (25 cm)

Amplifier configuration: Sampling rate adjustable to 20 khz Capacitance, leak, series resistance compensation

Temperature control: Ambient to 40ºC

Cell recording format; 20 cells per ensemble recording, 2X redundancy

Software

Operation modules: Protocol editor, run table, assay development mode, recording visualization, analysis, and data export

Operating system: Windows 7, XP, Vista

External compatibility

 Liquid handling automation: Compatible with most liquid handlers, SDK available

 Multiplexing ability: Integrate up to 4 readers per liquid handler

Applications:

• Ion Channel Research & Drug Screening:
  Perfect for high-throughput screening of ion channels, ligand-gated and voltage-gated ion channel assays, and drug discovery studies.
• Cardiac Safety Profiling (hERG):
  Ideal for hERG testing and other cardiac safety studies, helping evaluate the potential cardiac risks of drug compounds.
• Pharmacology & Toxicology:
  Ideal for pharmacology studies, toxicology screening, and cardiac ion channel safety.
• Assay Development & Optimization:
  Supports the development of complex assays, including ligand binding, allosteric modulation, and multi-agonist assays.

Included:

• Fluxion IonFlux HT Automated Patch Clamp System
• Microfluidic Plates (compatible with 96-well and 384-well plates)
• Control Software and Data Acquisition Package
• Temperature Control Unit
• Electrode Mounting and Maintenance Tools
• Standard Warranty (1 Year)

The IonFlux HT system is a high-performance solution for your ion channel research, offering unmatched throughput, economical cost per data point, and seamless integration into existing lab automation workflows. Perfect for drug discovery, pharmacology studies, and safety profiling, the IonFlux HT is a must-have tool for accelerating your research and ensuring reliable, high-quality results.

The primary difference between the Fluxion IonFlux 16 and IonFlux HT automated patch clamp systems is the number of independent amplifier channels, with the IonFlux HT having significantly more, allowing for much higher throughput in high-throughput screening applications compared to the IonFlux 16 which is better suited for standard ion channel research and assay development.

Key points:

Channel count: IonFlux 16 has 16 amplifier channels, while IonFlux HT has 64 channels.

Application: IonFlux 16 is ideal for standard ion channel research and assay development, while IonFlux HT is designed for high-throughput screening of ion channel targets.

Throughput: Due to its higher channel count, IonFlux HT can process a much larger number of samples per run compared to IonFlux 16.